SB-616234 is a selective serotonin 5-HT1B receptor antagonist. In terms of affinity, it shows 50-fold selectivity for the serotonin 5-HT1B receptor over the serotonin 5-HT1D receptor and greater than 100-fold selectivity for the serotonin 5-HT1B receptor over other serotonin receptors.
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