RU-27251, also known as 3,5-secoergoline or as 4-piperidin-3-yl-1H-indole, is a serotonin receptor modulator and dopamine receptor agonist of the partial ergoline family.<ref name="Osman_1987"> Its affinity (KD) for the dopamine D2high receptor was 72nM and for the dopamine D2low receptor was 11,600nM.
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