2-APBT is a monoamine releasing agent (MRA) of the benzothiophene family. It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC50 values of 8.9nM for serotonin, 21.6nM for norepinephrine, and 38.6nM for dopamine in rat brain synaptosomes.
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