PRX-03140 is an orally-bioavailable selective partial agonist to the 5-Hydroxytryptamine receptor 4 (5-HT4) and a ligand for the Sigma-1 and Sigma-2 receptors. PRX-03140 is a partial agonist (18% relative to 5-HT ) of the 5-HT4 receptor that was developed by EPIX Pharmaceuticals for Alzheimer's disease.
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