Lennoxamine is an isoindolobenzazepine alkaloid, originally isolated from the Chilean barberry, Berberis darwinii. Lennoxamine has been synthesised from 6-bromopiperonal in 9 steps; ; from 3-(3,4-methylenedioxybenzylidene)-6,7-dimsthoxyphthalide in 4 or 5 steps; and from 2,3-dimethoxybenzoic acid in 8 steps.
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